Wierd
Hi Tim,
A few things come to mind. First, how did you determine your angles were different tack to tack? Compass heading? GPS heading? Wind angle?
Assuming it was the usual either compass or app wind angle, then current would have no effect. The first thing is to make sure the rig is in the center of the boat. Just sight up the mast along the mainsail track and make sure it looks straight and not off to one side or the other-then, to confirm, take the main halyard shackle down to one of the chainplates, and cleat it off at, say, the top of the U-bolt on deck. Then move across the boom and pull the halyard down to the same spot on the other side. If the halyard shackle rests on the deck, the mast is off to THAT side. If it rests higher off the deck, it is off to the OTHER side. If so, adjust the rigging accordingly.
If this just happened, and has not happened before, it is probably not the mast tune, but genoa lead. The most likely reason is that someone moved one of the Genoa cars forward or way back-making the sail impossible to trim correctly. On the "good tack", make sure the lead is right (as described in many of my posts)-so that the inside telltales "break" at the same time as you head up from close hauled. Then put the other side's car in the same spot. Take 2 aspirin, and call me in the morning.
Or, let me know if any of this fits your situation. If not, come back and we will keep working it through.
Good luck,
S