Off-hand I would think a 50 micron mesh would be useful for something like a watermaker, but overkill for engine cooling. But if you get sufficient flow through it with your pump, why not?
My boat had no strainer at all. When it was new, there was some kind of screen outside the through-hull but that was long gone. I added a very inexpensive plastic unit that was probably intended for a wash-down pump. It worked, but wasn't very durable - after cleaning it a few times the screen wouldn't properly seal again. Later, I upgraded to a Groco filter when the budget allowed.