If you've got a tow package you're probably good to go but, of course, you'll still want to check max towing weights. If you don't have a tow package then you'll need to make sure you've got a hitch properly rated for the weight and, even with a tow package, it's worth double-checking. You also want to consider your transmission. If you don't have a tow package then you don't have the larger transmission oil cooler. If you're not going a long way then that may not matter so much but if you are, or if you're going to climb any long and/or steep grades, you run the risk of cooking your tranny. Engine, drive shaft, u-joints, rear end and brakes (because the trailer is equipped with brakes) are secondary considerations to the hitch and the tranny.