You can connect a "stand-alone" GPS receiver/antenna to a VHF radio; I just did it with a new Standard Horizon GX2150 Matrix AIS+ radio. However, I used Standard Horizon's GPS receiver/antenna product. You should, however, be able to use any GPS receiver/antenna that will give your radio the NMEA data sentences and baud rate it requires. That's the trick, matching up the radio to the GPS receiver. (It seems that most antennas send a variety of data sentences.)
I was a little disappointed that there was no direct mating plug from the antenna to the radio. I had to cut off the plug on the antenna cable and wire the antenna to the radio via a terminal block. The wires are very small; 28 gauge. A friend said this is because it is a low-voltage device. (I guess the Standard Horizon GPS Smart Antenna is meant to be connected to some Standard Horizon chart plotter that has a mating plug.)
Anyway, it works. I have attached two diagrams Standard Horizon gave me to make the connections. They will probably be different than what you need, but a useful reference nonetheless. Following is the email I received from Standard Horizon regarding the connections:
The Standard Horizon smart antenna can be connected directly to the radio; however, the connector needs to be cut off. Afterwards, you would need to take the red and black wires to a 12 volt power source. The brown wire from the antenna would be connected to the radio's blue wire. The yellow wire from the antenna would be connected to the radio's green wire.
Because whenever the antenna is connected to 12 volts the antenna is on and drawing power, it is important to have a method of disconnecting it from power when not in use. This can be accomplished by installing a switch or by connecting it to a panel that is disconnected from the battery when the boat is not in use. Please see the picture below:
I accomplished adding a switching function to the antenna power connection by wiring it to the same breaker that powers the radio; unless the breaker for the radio is turned on the antenna gets no power. I figured the current draw for the antenna is so small it wouldn't affect the radio.
One note, I imagine the 5 VDC power that the receiver you reference needs will require you to step down the usual 12 VDC boat current to 5 VDC via some sort of transformer.